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All product prices are in US dollars.
US Brand Name Actonel
Generic Name Risedronate sodium
Other Brand Name Actonel
Packing 6
Manufacturer Sanofi Aventis, Sanofi India
Form Tablet
Strength 5mg, 35mg, 75mg
Country India

  • 6 Tabs 75 mg $168.00
  • 4 tabs 35 mg $39.00
  • 28 Tabs 5 mg $97.55
Available online

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Details

Introduction

The drug Risedronate sodium is a form of bisphosphonates which can be used in putting the calcium into the bony structures by reducing the osteoclastic activity and increasing the binding of calcium with hydroxyapatite in the bones. It is used in the treatment of osteoporosis that occurs due to reduction in the estrogen hormones in post menopausal women so that their bony structures are strengthened and there is lowering of fracture in the osteoporotic bones.


Use

The drug is used for the purpose of recovering from osteoporosis in post menopausal women so that they do not suffer from fractures in the future. It helps also in other bone conditions where there is requirement to increase the calcium deposition into the bones. Since the action is directly in the bones, Risedronate sodium is a good agent for this activity. It is also used in Paget's disease and in corticosteroid induced osteoporosis.


Side effects

More common symptoms reported with the use of this drug are back pain, shoulder pain, arthralgia and dyspepsia. Hypersentivitiy reactions in form of allergic rashes are also seen. Femur and dental bone problems can be seen but is rare. Inflammatory conditions of the eyes are seen rarely.


Contraindication

The drug of Risedronate sodium is contraindicated in case the patient is allergic to the drug or any other component inside. Those who are not able to stand or sit upright for 30 minutes and those having liver or kidney problems should avoid taking the drug. People with low calcium level should not be prescribed the drug.


storage

The drug is to be stored in temperatures ranging from 25-30 deg C and should be kept away from light, heat and moisture. It should be kept away from the children also.


Composition

The tablet of Actonel contains 75 mg of Risedronate sodium along with other inactive ingredients that can be binders or stabilisers such as crospovidone, polyethylene glycol, cellulose, lactose monohydrate, etc.


Important Precautions

While taking the drug orally, the drug should not be chewed or broken and it should be gulped at once with water. In case of peptic disease or esophageal problems, the condition should be reported to the doctor. Use of any other drugs or bisphosphonates in particular should be mentioned to the doctor. Dental procedures or surgery should not be done during the taking of the drug as osteonecrosis of jaw has been reported. In case, severe bone or muscle pain occurs, the drug should be withdrawn. Patients with new thigh or bone pain should be evaluated for any problems related to fracture.


Dosage and administration

The 75 mg tablet of Risedronate sodium is to be taken for two consecutive days once in a month so that the total dose in a month is 150 mg. The drug should be taken orally, early in morning before eating or drinking anything, along with plenty of water. It should be swallowed at once and should not be chewed or broken in the mouth. It should be taken 30 minutes before taking anything and one should not lie down for 30 minutes after taking the drug.