Metformin, Careprost, Sildenafil, Tadalafil

All product prices are in US dollars.
US Brand Name Avandamet
Generic Name Rosiglitazone maleate, metformin HCl
Other Brand Name Avandamet
Packing 56
Manufacturer GSK
Form Tablet
Strength 2mg, 1,000mg

  • 56 tabs 2 mg/1000 mg $39.76
Out of Stock. Please contact us for Availability.
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The drug of Avandamet contains a combination of the antidiabetic drugs which are given for a better control of the blood sugar level. The two components work with different mechanisms of action to combinedly lower the plasma glucose level and therefore has been packaged in the same tablet. The tablet is given in people with Type 2 diabetes mellitus.


The tablet containing Rosiglitazone maleate and Metformin HCl is used in Type 2 diabetes mellitus so that it helps in lowering the blood glucose levels. It is a common oral hypoglycaemic agent that is being used nowadays and has given the user increased options from among the various oral antidiabetic agents. It can be given in obese patients who are having an increase in their weights.

Side effects

Use of the drug leads to the occurrence of some common side effects such as cold like symptoms, diarrhea, dizziness, headache, indigestion, nausea, vomiting, stomach upset, etc. Some rare side effects are allergy to the drug components, blurred vision, dark urine, lightheadedness, weight gain, and many others which should be told to the prescribing doctor so that the dosage can be changed or drugs can be altered. Lactic acidosis and liver dysfunctions are related to the individual components.


The drug is not to be used in cases of type 1 diabetes mellitus, as in this condition, pancreatic tissues are not secreting insulin. In cases of heart failure, severe kidney or liver disease, during surgery, severe infection, etc, the drug should not be used as the insulin level is either not controlled properly, or the drug can cause further side effects.


The drug is stored at temperatures of 25 deg C within a range of 15-30 deg C. It should be stored away from light and moisture and away from the reach of children and not in the bathrooms.


The drug tablet contains the oral hypoglycaemic drugs of Rosiglitazone maleate belonging to thiazolidinedione family while Metformin HCl belongs to the biguanide family. They are present in concentrations of 2 mg of Rosiglitazone and 1000 mg of Metformin. Along with the drug bases, there are other chemicals that are used as binding agents and preservatives such as magnesium stearate, polyethylene glycol, sodium starch glycolate and iron oxides.

Important Precautions

In case of pregnancy developing during the taking of the drug or in breast feeding mothers, the information should be shared with the doctor. Allergies to food and other drugs, even these two compositions should be informed. If any other drugs or medications are being used simultaneously, then these drugs are given with care. Use of alcohol or deterioration in the condition of any pre-existing disease is to be immediately reported to the doctor. The hypoglycaemia is not very common with this drug, but should still be watched out for and therefore meals should not be skipped if they are being administered. Any complications like bone fracture or impending surgery requires extra care in the administration of the drug. Development of lactic acidosis is common due to the Metformin component, which requires immediate attention.

Dosage and administration

Rosiglitazone and metformin are present in concentrations of 2 mg and 1000 mg respectively and given as one tablet day. It is administered before meals everyday, preferably at the same time. Two tablets are not advised to be taken simultaneously in case of missed doses as it will lower the blood glucose drastically.