Metformin, Careprost, Sildenafil, Tadalafil

All product prices are in US dollars.
US Brand Name Avodart
Generic Name Dutasteride
Other Brand Name Avodart
Packing 30
Manufacturer GSK
Form Capsule
Strength 0.5 mg
Country India

  • 30 Capsule 0.5 mg $56.70
Available online
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Details

Introduction

Dutasteride is used in the treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH). It reduces the risk of acute urinary retention (AUR) and surgery in patients with moderate or severe symptoms of BPH.


Use

Dutasteride is used in treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH). The drug reduces the risk of acute urinary retention (AUR) and surgery in patients with moderate or severe symptoms of BPH.


Side effects

In clinical Phase III, placebo-controlled, about 19% of the 2167 patients who received dutasteride experienced adverse reactions. Most events were mild to moderate and occurred in the reproductive system. In controlled clinical trials during the first year of treatment have been reported some adverse reactions with an incidence greater than placebo-treated groups including Impotence, Altered (decreased) libido, Ejaculation alterations, Gynecomastia.


Contraindication

Dutasteride is contraindicated in women, children and adolescents. Dutasteride is contraindicated in patients with hypersensitivity to dutasteride, other 5-alpha reductase inhibitors or any of the recipients. Dutasteride is contraindicated in patients with hepatic impairment.


storage

Store it at temperatures below 30 ° C and in the original packaging.


Composition

Dutasteride Capsule contents: mono-di-glycerides of caprylic / capric acid, butylatedhydroxytoluene. Capsule: gelatin, glycerol, titanium dioxide (E171), yellow (E172). Burning red ink: red iron oxide (E172), polyvinyl acetoftalat, macrogol, propylene glycol.


Important Precautions

In patients with BPH, Digital rectal examination and other evaluations for prostate cancer should be performed before initiating therapy with Dutasteride and periodically thereafter. Dutasteride is absorbed through the skin, so women, children and adolescents should avoid contact with leaking capsules. If contact is made with leaking capsules, the contact area should be washed immediately with soap and water. In patients with hepatic impairment have not been studied Dutasteride. In patients with mild or moderate, Dutasteride will be made with caution.


Dosage and administration

Adults (including elderly) the recommended dose of Dutasteride is dutasteride 0.5 mg (one capsule) taken orally as a single dose. Capsules should be swallowed whole and can be taken with or without food. Obtaining the response to treatment may take up to six months, although an improvement can be seen still in an early stage. In the elderly, no dosage adjustment is necessary. Renal failure it was studied the effect of renal impairment on dutasteride pharmacokinetics. In patients with renal impairment, no dosage adjustment is expected. Hepatic insufficiency It was studied the effect of hepatic impairment on dutasteride pharmacokinetics, so caution should be used in patients with mild-moderate. In patients with severe hepatic impairment is contraindicated Dutasteride.