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All product prices are in US dollars.
US Brand Name Comtan
Generic Name Entacapone
Other Brand Name Comtess
Packing 30
Manufacturer Orion Pharma
Form Tablet
Strength 200mg

  • 30 tabs 200mg $82.50
Available online
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Entacapone is a drug that known as a nitrocatechols. This medicine works as catechol-o-methyl tranferase inhibitor. It is more effective if you used in combination with levodopa and carbidopa. This medicine helps to treat the end-of-dose 'wearing-off' symptoms of Parkinson's disease. Parkinson's disease is believed to be due to a lack of an important chemical in the brain called dopamine. The symptoms of Parkinson disease are caused by degeneration of neurons that release the neurotransmitter dopamine, resulting in insufficient levels. Neurotransmitters are chemicals that carry messages from one neuron to another or from a neuron to a muscle. Entacapone prolongs the action of levodopa by approximately one to two and a half hours, making its action more predictable.


This medicine use treating of parkinson's disease which can block a certain natural's substance that breaks down the levodopa in the body. Use this medicine regularly to get the best result.

Side effects

Every medicine has its side effects. Entacapone have side effects which include vomiting, urine discoloration, confusion, taste changes, fatigue, muscle cramps, lower back pain, twisting, and tightness in chest, bacterial infection, increased sweating, tiredness, abdominal pain, nausea, diarrhea, drowsiness and dry mouth. Some side effect needs to be reported to your doctor such as; a mental change, unusual urges, fever, muscles stiffness, muscle weakness, trouble breathing, rash and itching. This side effect is not complete, for the complete lists kindly visit your doctor to have.


Entacapone is contraindicated to those patients who have hypersensitivity of any component of this medicine also to those patients who are planning to become pregnant and pregnant. To know your standing about this medicine you may consult your doctor.


Entacapone can be stored at room temperature at 77 degrees F. Keep this medicine in the container that tightly closed. Keep away from any heat produce by the sun and any moisture. Keep all medicine away from the reach of the children. Do not flush any medicine in the toilet.


Entacapone is a medicine which is in the form of tablet for oral administration with the strength of 200 mg. This medicine contains microcrystalline cellulose, croscarmellose sodium, hydroxypropyl methylcellulose, and 855 of glycerol, magnesium stearate, red oxide, mannitol, and hydrogenated vegetable oil, 805 of polysorbate, sucrose, yellow iron oxide and titanium dioxide.

Important Precautions

Before taking this tablet you must consult first to your doctor because there are ingredients that may cause you to have allergy. Also you need to tell your doctor if you have the history of alcoholism, low blood pressure, liver problems and planning to be pregnant. Do not share your medicine with other patients because it might give them side effects due to incompatibility of the disease and to the medicine. Avoid drinking alcohol, which can increase some of the side effects of entacapone. Always see the expiration date.

Dosage and administration

This medicine may require 200 mg for intake. The maximum recommended doses 200 mg ten times a day or as prescribed by your doctor. Follow the prescription given by the doctor. Do not just increase or decreased it without their consent.