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All product prices are in US dollars.
US Brand Name Generic Boniva
Generic Name Ibandronic Acid
Other Brand Name Bondronat, Bondria, Idrofos
Packing 28
Manufacturer Sun Pharma, Cipla, Roche Products India
Form Tablet
Strength 50mg
Country India

  • 3 tabs 150mg $39.00
Available online
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Details

Introduction

Bondronat tablets or Ibandronic acid tablets are meant for preventing skeletal fractures or bone pathology in patients with metastatic bone disease. As it helps in the formation of new bones, it is to be used in such patients whose calcium from the bones has been lost and they have increased chances of fracture. This is of better use in bony metastasis of cancer where bone resorption is faster than bone formation. These drugs help by reducing the osteoclastic bone resorption and helps in quickening the bone formation process.


Use

Mainly for the purpose of treatment of bone pain in cancer patients, the tablets are used as these patients have their calcium lost from the bones. In metastatic bone diseases, ibandronic acid tablet is used. The drug is also used to reduce the risk of any kind of skeletal or bone problems in malignant diseases apart from reducing the chances of fracture. To prevent the bone pain due to radiation therapy, the drug can also be used.


Side effects

Most common side effects for ibandronic acid are dyspepsia and hypocalcemia. Sometimes flu like syndrome has been reported with symptoms of malaise, fever, rigor, chills, etc. Sometimes, the calcium and phosphate levels of the blood are lowered leading to problems of hypocalcemia. Broncho-constriction or wheezing like symptoms are usually seen.


Contraindication

The drug is not to be used in pregnancy and in breast feeding mothers as there are not much of clinical experience. In case of patients suffering from allergy to the drug or its constituents, the drug is not to be given. It is usually not prescribed for children below the age of 12 years.


storage

The tablets of this drug should be stored at room temperatures not exceeding 30 deg C. It should be kept dry and away from the reach of children.


Composition

The tablet form is a film coated tablet of 50 mg Ibandronic acid and consists of lactose monohydrate as the primary excipient. The drug can also be present as Ibandronic sodium monohydrate.


Important Precautions

Hypocalcemia is to be properly treated when the ibandronic tablet is to be started while vitamin D and calcium therapy can be required. As the oral form of bisphosphonates has been considered to be causing esophageal ulcers, they should not be chewed or broken inside the mouth and food should not be taken along with the drug. One should not be moving about within 30 minutes of taking the drug. NSAIDs should not be given along with it as they both might cause the problems of gastric ulcers. Renal and hepatic problems during the drug administration should be taken care of.


Dosage and administration

The tablet form of the drug is to taken orally in an empty stomach after an overnight fast. It should be taken with plenty of water and no other diet. It should be gulped when standing or sitting and the person should maintain the position for the next 30 minutes. The drug is advised to be administered orally 50 mg tablet daily.