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US Brand Name Fosamax
Generic Name Alendronate
Other Brand Name OSTEOFOS
Manufacturer CIPLA
Packing 10, 4
Form Pills
Strength 10 mg, 35MG, 70MG

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Details

Introduction

Generic Fosamax or commercially popular Alendronate is given to postmenopausal women for the treatment and avoidance of osteoporosis. It comes from the group of medications called bisphosphonates that is used to treat the problem of reduced density of bone. It is also used in the treatment of bone pain that occurs due to other health problems such as metastatic breast cancer, Paget's disease and multiple myeloma. Alendronate has been approved by the FDA in September 1995.


Use

Alendronate is widely used for the treatment and prevention of types of bone loss (osteoporosis). Specifically, it is also used for the treating prophylaxis, and female as well as male osteoporosis. In addition, it is also recommended for the prevention and treatment of Paget's disease and corticosteroid-related osteoporosis along with supplements of calcium and vitamin D.


Side effects

Stomach ache, constipation, gas, and nausea are some of the common side-effects. Make sure that you inform your doctor about these changes. However, immediate attention of your doctor is recommended, if you suffer through the more severe side effects such as jaw pain, black stools, increased pain in joint, bone and muscle, swelling of hands, ankles, feet, arms, and finally vomit that may appear as coffee grounds.


storage

Alendronate can be safely stored at room temperature between 59 and 86 degrees. It should be kept away from light as well as moisture and hence, should not be kept in the bathroom. Make sure to properly discard your medication if it runs beyond the mentioned expiry date.


Dosage and administration

Generic Fosamax or Alendronate is to be taken orally. The medicine should be taken with water only and not with any other drink such as juice, coffee, milk, tea etc. The dosage prescribed normally is one per day. After taking the medicine, the patient is not supposed to eat or drink anything for next 30 minutes. Also, one should not lie down for at least 30 minutes after taking Fosamax.


Overdosage

Overdosing of Alendronate may result in disturbed health conditions including severe stomach ache, mental/mood changes, hurting heartburn, pain in the esophagus (chest pain), muscle failing. Immediate medical assistance should be taken in such circumstances.


Clinical performance

Steep normalization in the rate of bone turnover and considerable improvement in BMD (bone mineral density) of the spine, hip, wrist and total bodyhave been reported during the use of Fosamax to cure post-menopausal women. Fosamax also shows significant reductions in the ailments of vertebral (spine) fractures, wrist fractures, hip fractures, and all non-vertebral fractures in the women. In a woman who diganosed with highest risk of fracture (by virtue of pre-existing vertebral fractures) in the Fracture Intervention Trial, Fosamax 5 mg/day for two years followed by 10 mg/day for the third year (plus calcium and vitamin D) shows good improvements and 50% reductions in fractures of the spine, hip, and wrist is also reported during the treatment. The results are motivating when compared with the control group taking placebos plus calcium and vitamin D to diagnose the ailments.