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US Brand Name Lipitor
Generic Name Atorvastatin
Other Brand Name Lipvas, Atorlip, Omnitor, Biostat
Manufacturer Torrent, BioGeniccs, ZYDUS, INTAS, Ranbaxy, SUN PHARMA, Cipla, Sava medica
Packing 10
Form Tablet
Strength 20 mg, 10 mg, 5 MG, 40 mg, 20 mg, 10 mg

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Details

Introduction

Atorvastatin or commercially known as Lipitor, is a medication that comes from the group of drugs called HMG-CoA reductase inhibitors or "satins." The medication helps in reducing and decelerating the production of high levels of cholesterol and other types of harmful fats in the blood. As medication, it is prescribed with proper low fat diet and regular physical exercise. Patients taking Lipitor are also asked to reduce weight to stay away from the threat of heart attack and strokes.


Use

Atorvastatin helps in reducing the increased level of total cholesterol, LDL and triglycerides. It is used to boost up the quantity of HDL cholesterol. The overall effectiveness of the drug depends on the dose taken. It keeps at distance dangerous health problems such as angina, heart attack, stroke, congestive heart failure, and revascularization procedures in patients dealing with coronary heart disease. Also, it diminishes the threat of myocardial infarction, angina, stroke and revascularization procedures in adults with many risk factors for coronary artery disease. It is also given to patients suffering from type 2 diabetes for the same reason.


Side effects

Commonly noticed side effects of Lipitor are fever, itching, tiredness, nausea, chest pain, weakness, muscle pain, loss of appetite, rash, flu-like symptoms, hoarseness, stomach ache (in the right side) and swelling of the face, lips, eyes, throat, tongue, hands, feet, and ankles. Some serious adverse effect of Lipitor may include problems of joint pain, gas, constipation, headache and diarrhea.


storage

Lipitor tablets can be best maintained at room temperature ranging from 20° to 25°C or 68° to 77°F.


Composition

LIPITOR or atorvastatin calcium Tablets are composed of 10, 20, 40, or 80 mg atorvastatin along with many other inactive ingredients counting as calcium carbonate, candelilla wax, croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, simethicone emulsion and lactose monohydrate .


Dosage and administration

Mostly, Atorvastatin is given with the prescription of once daily. The typical starting dose is 10-20 mg/day. It normally goes up to 80 mg per day. Patients aiming to achieve over a 45% reduction in LDL cholesterol are recommended to begin with 40 mg daily. It can be taken with or without food, with almost no restriction of time.


Overdosage

If you see severe side-effects causing due to the overdose, contact the nearest poison control center or emergency room instantly. Do not try to make up for a missed dose by taking twice the amount prescribed for a day.


Clinical performance

A number of medical researches and clinical studies have established the fact that improved levels of total-C, LDL-C, and apo B (a membrane complex for LDL-C) promote human atherosclerosis with an immediate impact. In the very same manner, reduced levels of HDL-C (and its transport complex, apo A) are the primary factors behind the development of atherosclerosis. Epidemiologic investigations have proved that most talked cardiovascular morbidity and mortality vary directly with the presence of levels of total-C and LDL-C, and inversely with the level of HDL-C as well.