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US Brand Name Prograf
Generic Name Tacrolimus
Other Brand Name Tacromus
Manufacturer Zydus Cadila
Packing 10
Form Capsule
Strength 0.5 mg, 1 mg, 2 mg, 3 mg, 5 mg

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The immune system of body helps in fighting against the infections. Sometimes, when heart, liver or kidney transplantation occurs, the body’s immune system rejects it as it treats new organ as an invader. In order to prevent the rejection chances of liver, heart or kidney transplant, generic Prograf is recommended by doctors. The drug is available in 0.5mg, 1mg, 2mg, 3mg, 4mg and 5mg capsule form.


Generic Prograf belongs to group of drugs known as immunosuppressant. The drug is mainly used for treating and preventing the cases of rejection of liver transplants. The drug works by blocking the action of calcineurin, a substance that is available in T-lymphocytes (white blood cells). These white blood cells produce lymphokines when any foreign substance is detected in the body. Because immune system is not able to recognize them, so it starts attacking the transplant organ. When a person takes the drug, the activity of T-lymphocytes gets suppressed, thereby preventing the chances of rejection of transplantation.

Side effects

Some of the possible side-effects of generic Prograf include chest pain, difficulty in breathing, increased bleeding, cough, decreased urination, abdominal pain, muscle weakness, constipation, loss of appetite, etc. These side-effects go away with the regular dosage. However, if these symptoms remain persistent for long time, seek medical attention immediately.


For maintaining effectiveness of the drug, store it in room temperature. Keep the capsules away from direct light, heat and moisture. Avoid storing the drug near the bathroom, kitchen or damp places.


Tacrolimus acts as main ingredient in the drug.

Dosage and administration

The drug can be taken intravenously or orally. For obtaining the desired results, it is important to take the dosage in prescribed form. Do not take overdosage and missed dosage. The Tacromilus capsule is taken after every 12 hours. The drug works in the best manner when it is taken same time every day. The dosage can be increased or decreased by doctor for obtaining the best result. An important note necessary to highlight is that dosage may vary from person to person.


It is important to discuss the medical facts with healthcare professional before taking the drug. It is due to the fact that there are certain drugs which may interact with generic Prograf. Additionally, tell healthcare professionals if you are allergic with any drug. Similarly, disclosure about any medicine a person is taking is also important, especially if he is taking astemizole, dofetillide, ziprasidone, ibutilide, etc.


Avoid taking overdosage of the drug as it may lead to some harmful effects. Moreover, if any person takes overdosage of the drug, report to doctor immediately.