Metformin, Careprost, Sildenafil, Tadalafil

All product prices are in US dollars.
US Brand Name Generic Synalar
Generic Name Fluocinolone Acetonide
Other Brand Name Flucort
Packing 20g
Manufacturer Glenmark Pharma
Form Gel/ Cream
Strength 0.025%w/w
Country India

  • Cream 20g 0.025% $3.99
Available online
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Details

Introduction

Fluocinolone Acetonide is a synthetic corticosteroid, generally used topically to reduce the skin inflammation and relive itching. It is a synthetic hydrocortisone derivative. It also has the properties like anti-inflammatory, antipruritic and vasoconstrictive properties. It acts by induction of phospholipase A2 inhibitory proteins, which are called as lipocorteins. Lipocortins control the biosynthesis of the potent mediators or inflammation like leukotrienes, prostaglandins and lipid acids by inhibiting the release of their common precursor that is Arachidonic acid in the lipooxygenase path of the lipid metabolism. Arachidonic acid is secreted from the membrane phospholipids by phospholipase A2.


Use

It is indicated to relieve the inflammatory and pruritic manifestations of corticosteroid-responsive dermatosis. Because of its anti-inflammatory properties, the topical steroid can be applied in layers over areas which have burning or itching surfaces. Even on skin infections these are possible to be applied along with other specific drugs as it helps in reducing the overall inflammatory region.


Side effects

Like other drugs fluocinoline acetonide also has some of the adverse impact on the human body. These adverse effects include some allergic reactions due to the contents of the cream such as itching, rashes, urticaria, etc. Though the steroid doesnt cause side effects unless it is systemically absorbed, some side effects can be seen such as burning, itching, hypertrichiosis, secondary infection and skin atrophy in the long run.


Contraindication

This should not be applied when a person has hypersensitive to any components of this drug. It also should not be applied in the viral infections in the cornea, conjunctiva, including epithelial herpes simplex kertitis, varicella and vaccinia and also in the mycobacterial infections of the eyes and fungal diseases of ocular structures.


storage

It is stored in the dry and cool place in the normal room temperature ranging from 15 degree Celsius to 30 degree Celsius. It should not be exposed to the direct sunlight and moisture. It should be kept away from the reach of the children and the pets.


Composition

This gel or the cream is composed of the anti-inflammatory, antipruritic and vasoconstrictive agent like Fluocinolone Acetonide. It is present in the strength of 0.025% w/w of the drug in the gel or cream.


Important Precautions

Before prescribing this gel to the patient, all the contraindicative cases should be ruled out. It should not be applied in the face particularly in the region nearer to the eyes. After the application of this drug hands should be washed properly with maximum amount of cool water. If it comes in contact with eyes then, the eye should be washed properly. Before using this gel the expiry date should be seen.


Dosage and administration

It is applied topically on the affected area two three times in a day to get a better result. After using this, hand should be washed properly with enough amount of cool water. The cream shouldn't be rubbed deeply and it is only to be applied.