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All product prices are in US dollars.
US Brand Name Havrix Inj
Generic Name Hepatitis A Virus
Other Brand Name Havrix Inj
Packing 1
Manufacturer GSK
Form Injection
Strength 720IU, 1440IU
Country India

  • Pead 720 Elisa U Injection $46.21
  • Adult 1440 Elisa U Injection $69.38
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Details

Introduction

The hepatitis A virus vaccine is a means to prevent the diseases due to hepatitis A virus in individuals and is a form of active immunisation. When the vaccine is given to people, the virus gets multiplied and mounts an immunity against the external infections with the virus A only and not against the other hepatitis viruses. For those people who are more prone to get exposed to hepatitis A virus, the vaccine is a good way to prevent the infection.


Use

Active immunisation with the hepatitis A virus vaccine is done to prevent infection with the strain A. Those who are at a greater risk of getting the infection are to be administered the drug. These people include travellers to endemic areas such as Asia, Africa, central and south America, etc. People in the armed forces are to be administered with the vaccine as they live in close quarters. Individuals with multiple sexual partners, homosexuals, haemophiliacs, injectable drug users, and medical personnel are more prone also. People who come in close contact with those who already have the disease should get vaccinated. Those who are already having liver diseases and have a lower immunity should receive the vaccine.


Side effects

In children, the common side effects observed with the vaccine are injected site allergic or local reactions. Soreness and headaches are commonly seen. Other local reactions are pain, redness and burning at the site of vaccination. Generalised symptoms can be dizziness, drowsiness, irritability and loss of appetite.


Contraindication

Allergic reactions of the vaccine in patients are to be taken extreme care and those who have demonstrated such interactions are not to be administered with the vaccine. The hypersensitivity is possible with any of the components of the vaccine injection, including neomycin.


storage

The vaccine is stored at 2-8 deg C and not allowed to freeze, in which case it has to be rejected. The vaccine is to be given as it is and not diluted.


Composition

Each vaccine of 1 ml volume contains the inactive Hepatitis A virus antigen in the concentration of 1440 EL.U. and is adsorbed on 0.5 mg of aluminium hydroxide. Along with the vial, there is also a prefilled syringe.


Important Precautions

The use of injection syringes with latex caps can be a reason for the allergy seen in latex sensitive individuals. There should be adequate set up for managing any kind of allergic reaction. Patients who are immunocompromised will have to be careful when vaccine is administered. For patients who have an unrecognised immunocompetencies or hepatitis infection already, will not respond to the vaccine because the incubation period of the vaccine is long. Care should be taken when the vaccine is to be given to pregnant females, nursing mothers and elderly age group people.


Dosage and administration

The primary immunisation is done by administering the vaccine in the individuals above 19 years of age at the dose of 1 ml. Two doses of the hepatitis A vaccine is administered, the second dose of 1 ml given after a period of 6 to 12 months. For children, the dose is 0.5 ml for both the doses. The vaccine is given into the upper deltoid muscle of the arm. The vaccine is given by intramuscular route only and the intravenous, subcutaneous and other routes are not chosen.