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All product prices are in US dollars.
US Brand Name
Generic Name Polymyxin B/ Chloramphenicol/ Dexamethasone
Other Brand Name Ocupol DX
Packing 5 ml
Manufacturer Intas Pharma, Centaur Pharma
Form Eye Drops, Eye/ Ear Drops
Strength (Per 1ml) Polymyxin B Sulfates 5000IU/ Chloramphenicol 4mg/ Dexamethasone 1mg
Country India

  • Eye/ Ear Drops 5ml Polymyxin B 5000IU/ml/ Chloramphenicol 4mg/ml/ Dexamethasone 1mg/ml $6.00
Available online
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Details

Introduction

It prevents the infections caused by the gram positive and gram negative bacteria in the eye. It also kills the bacteria in the eye and relieves the eye from the infections. Being bacteriostatic and cidal at high concentration, the drug helps in lowering the amount of infectious organisms in the corneal surface. The drug is also utilised for its antibacterial action to provide a prophylaxis effect.


Use

This ophthalmic preparation is used to prevent or to treat the infections in the eyes. In some of the conjunctival infections, the drops of polymyxin B and Chloramphenicol are used.


Side effects

Temporary burning sensation is felt in the eyes for some minutes at the initial application. The vision may be temporarily blurred and unstable after the application. A skin rash, itching, burning, pain, redness and swelling are seen in and around the eyes. In the severe form of the adverse effects the concern physician should be consulted.


Contraindication

It is contraindicated in the patient with having allergic reactions in the eyes after the administration of this ophthalmic solution in the eyes due to any of the ingredients of this preparation. It also contraindicated in the cases like keratitis, dendritic, epithelial herpes, vaccinia, varicella, viral infections of the cornea and conjunctiva. Care should be taken to not allow the drug to be given during viral infections as the infection is not controlled by these antibacterial drugs.


storage

It is stored in the normal room temperature varying from a range of 15 degree Celsius to the 30 degree Celsius. Freezing, direct radiations should be avoided. It should be kept in the place away from the reach of the children and the pets.


Composition

This ophthalmic solution is composed of the active ingredients like Polymyxin B Sulfate in 10000 IU in 1 ml and Chloramphenicol in 1mg in 1 ml. Other inactive ingredients of this drug include benzalkonium chloride, sodium chloride, sulfuric acid, water and sodium hydroxide.


Important Precautions

Before using this ophthalmic solution, the physician should rule out other problems and infections in the eyes. After the application the patient should not handle the machineries and should not drive the vehicles. Before using the eye drop the expired date should be checked properly. In the clear case of eye infection it can be prescribed in the case of pregnancy and lactation.


Dosage and administration

One drop of this ophthalmic drop is put in the affected eye in an interval of three hours. More than one drop is also possible to be used but clinical trials suggest that no particular benefit is found with its administration.