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All product prices are in US dollars.
US Brand Name Risperdal Solution
Generic Name Risperidone
Other Brand Name RISPERDAL CONSTA L A INJ
Packing 1
Manufacturer CILAG AG (JOHNSON & JOHNSON)
Form Injection
Strength 25mg / 2ml

  • 1 mg/ 1 ml 60 ml $39.00
Available online
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Details

Introduction

This is a second generation or atypical antipsychotic pharmacological preparation used for the treatment of the psychiatric disorders like schizophrenia, schizoaffective disorder, bipolar disorders and autism. Other actions of this drug are weight gain, metabolic problems, tardive dyskinesis and neuroleptic malignant syndrome. Risperidone solution can also cause risk of death in the patients having dementia in the disorders like Parkinson disease and Alzheimer's disease. Unlike other atypical anti-psychotic drugs it is also used in the treatment of anxiety disorders like obsessive-compulsive disorders, disruptive behaviour in children, eating disorders, Tourette syndrome etc. It also effectively treats the symptoms of the psychosis associated with the use of the drug phencyclidine due to acute intoxication and chronic use.


Use

This drug is used in the treatment of particular psychiatric disorders like schizophrenia and bipolar disorder. This drug is able to restore the near normal activities of the daily living. It also restores the balanced secretion of the neurotransmitters in the brain.


Side effects

All the side effects of the drug are the extension of the pharmacological actions of the particular drug. The intra muscular administration of this injection is always associated with the unwanted weight gain. It may cause akathisia, sedation, dysphoria, sexual dysfunction, insomnia, hypotension, muscle cramp, myalgia, tremors, hyper salivation and constipation. It has the photosensitive effect and for which the patient under this treatment advised to avoid prolong exposure to the sun light. Pigmentations of the skin are also another side effect of the risperidone use. Pain, itching sensation can be felt in the site of injection.


Contraindication

This injection is contraindicated in the conditions like known allergic reaction towards the use of the risperidone solution. It is also not safe for the pregnant and lactating women. As it is secreted in the mother's breast milk it should not be given to the lactating mother. It should not be given to the children under the age of 5 years.


storage

It is stored in the normal room temperature ranging from 15 degree Celsius to the 30 degree Celsius. It should not be exposed to the direct sun light. It should be kept in the place away from the reach of the children and the pets.


Composition

This formulation is a white, free flowing powder that is available with dosage strength of 25mg/2ml in a vial. The dilute form of this drug is composed of the polysorbate, disodium hydrogen phosphate dehydrate, citric acid in the dry form, sodium chloride, sodium hydroxide, sodium carboxymethyl cellulose and water. The injection of risperidone vial contains 25 mg in 2 ml solution.


Important Precautions

The administration of this drug usually alters the mental alertness and therefore the patient should be advised not to drive the vehicles and handle the machineries. The initial and the subsequent dose should be reduced to half in the patients having renal and hepatic problems. This injection may cause hypotension as it has the alpha-blocking activity, so it should be administered with great cautions in the patients with cardiovascular problems. In this case the dose should be titrated gradually as per the physician's recommendation. If, hypotension occurs then, the dose should be reduced. Parkinson disease and Alzheimer's disease is always associated with dementia, so, this can cause death. Therefore, this should be administered with great cautions in PD and AD.


Dosage and administration

This is injected in the region like buttock or arm intramuscularly once in every two weeks. It should be injected in the alternate buttocks after two weeks. Intravenous administration should be strictly avoided. This injected solution of risperidone takes three weeks to initiate the functions. During the period after the initial administration up to three weeks the oral administration of the same drug is recommended.