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US Brand Name Tiomune
Generic Name Stavudine/Lamivudine/Nevirapine
Other Brand Name TIOMUNE
Manufacturer CIPLA
Packing 30
Form Tablet
Strength 30+150+200mg, 40+150+200mg

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Details

Introduction

Triomune is a grouping of 3 drugs commonly known as Nevirapine, Stavudine and lamivudine. It is meant to manage the Human Immunodeficiency Virus (HIV) infection. Nevirapine is a non-nucleoside reverse transcriptase inhibitor, whereas Stavudine and lamivudine comes from the nucleoside analogue class of antiretroviral drugs.


Use

Triomune is prescribed for the management of Human Immunodeficiency Virus (HIV) infection. Nevirapine works by openly inhibiting reverse transcriptase, whereas stavudine and lamivudine prevents and controls the growth of the DNA chain and inhibiting the reverse transcriptase of HIV. The highly recommended combination formulation enables patients to adhere to triple drug regimens, and thus, helps in enhancing compliance.


Side effects

Generic Tiomune is known to cause certain side effects. These include problems like fatigue, headache, loss of appetite, diarrhea, dizziness, upset stomach, cough, depression, stuffy nose. Some of the other known, rare and serious side effects are numbness, fever, vomiting, loss of weight, burning or pain in the hands or feet, difficulty moving your hands and feet, chills, painful red bumps on the skin, and swelling of the hands, feet, ankles, or lower legs. Such problems need instant medical attention.


storage

The medication can be stored at room temperature. It should be maintained away from the reach of children, pets, heat and light.


Composition

Lamivudine, stavudine and nevirapine are the active ingredients.


Important Precautions

Muscles problems and Myopathy, may occur due to this medication. The medicine should be discontinued if patients start suffering from rash accompanied by constitutional findings. If patients have serious liver function issues, or develop so on taking the medication, then stop its intake immediately. The medication may develop adverse effects on the unborn baby. Hence, tell your doctor if you are or are trying to get pregnant. Cases of lactic acidosis and hepatomegaly with steatosis, have been reported with use of these drugs or in combination. Triomune tablets are advised to pediatric patients.


Dosage and administration

The dose of Generic Triomune varies from patient to patient. The tablets are given as per the weight of the patient. The medication is not supposed to be administered to patients who have just started therapy with nevirapine.


Overdosage

In case of overdose suspicion, patients are recommended to call for medical assistance as soon as possible.